The importance of residual renal function for patients on dialysis. |
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| Authors: | Joanne M Bargman Thomas A Golper |
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| Affiliation: | University Health Network, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada. joanne.bargman@uhn.on.ca |
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| Abstract: | ![]()
| Introduction | It is the goal of every practitioner involved in the care ofdialysis patients to maximize survival and quality of life.The last two decades have seen a plethora of investigationsthat have sought to determine how this goal can be achieved.The bulk of the studies have, unfortunately, concentrated onsmall solute clearance and outcome (measured principally asmortality). The HEMO [1] and ADEMEX [2] studies suggested thatthis is not a fruitful avenue of investigation. However, theresidual kidney function in patients on dialysis, particularlyin those on peritoneal dialysis (PD), has proven to be a consistentand powerful predictor of mortality. We will review the evidence supporting the importance of residualrenal function (RRF) on outcome, propose some explanations asto why this relationship exists, and suggest ways to prolongthe renal function in dialysis patients. The evidence | Maiorca and colleagues were
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| Keywords: | adequacy of dialysis haemodialysis adequacy peritoneal dialysis |
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