Transmission of new bovine prion to mice |
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| Authors: | Baron Thierry G M Biacabe Anne-Gaëlle Bencsik Anna Langeveld Jan P M |
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| Affiliation: | *Agence Française de Sécurité Sanitaire des Aliments, Lyon, France;;†Central Institute for Animal Disease Control, Lelystad, the Netherlands |
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| Abstract: | ![]()
We previously reported that cattle were affected by a prion disorder that differed from bovine spongiform encephalopathy (BSE) by showing distinct molecular features of disease-associated protease-resistant prion protein (PrP(res). We show that intracerebral injection of such isolates into C57BL/6 mice produces a disease with preservation of PrP(res) molecular features distinct from BSE. |
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| Keywords: | Bovine spongiform encephalopathy prion cattle dispatch |
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