| 门脉高压性胃病与幽门螺杆菌感染 |
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| 引用本文： | 金珍婧,陈永胜,迟宝荣. 门脉高压性胃病与幽门螺杆菌感染[J]. 吉林大学学报(医学版), 2003, 29(2): 185-186 |
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| 作者姓名： | 金珍婧 陈永胜 迟宝荣 |
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| 作者单位： | 吉林大学第二医院消化内科,吉林,长春,130041;吉林大学第一医院消化内科 |
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| 摘 要： | 目的 :探讨幽门螺杆菌 ( Hp)在门脉高压性胃病 ( PHG)发生、发展中的作用及临床意义。方法 :Hp检测采用快速尿素酶试验 ( rapid urease test,RUT)和 Hp- PCR检测法。结果 :肝硬化门脉高压组 Hp阳性率显著低于慢性胃炎组、消化性溃疡组 ( P<0 .0 1 ) ;Hp感染和肝功能分级无显著相关性 ;PHG慢性活动性胃炎 Hp阳性率明显高于非活动性胃炎 ( P<0 .0 1 )。结论 :Hp感染不是PHG的主要致病因素 ,但 Hp感染和 PHG胃粘膜的慢性活动性胃炎密切相关
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| 关 键 词： | 肝硬化/病因学 门脉高压性胃病 螺杆菌 幽门/致病力 |
| 文章编号： | 1671-Ⅹ587(2003)02-0185-02 |
| 修稿时间： | 2002-03-04 |
Portal Hypertensive Gastropathy in Liver Cirrhosis and H.Pylori Infection |
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| JIN Zhen jing ,CHEN Yong sheng ,CHI Bao rong. Portal Hypertensive Gastropathy in Liver Cirrhosis and H.Pylori Infection[J]. Journal of Jilin University: Med Ed, 2003, 29(2): 185-186 |
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| Authors: | JIN Zhen jing CHEN Yong sheng CHI Bao rong |
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| Affiliation: | JIN Zhen jing 1,CHEN Yong sheng 1,CHI Bao rong 2 |
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| Abstract: | Objective: To study the effects and clinical significance of H. Pylori infection in portal hypertensive gastropathy. Methods: H. Pylori was detected by RUT and PCR. Results: H. Pylori infection rate in PHG was significantly lower than that in chronic gastritis and peptic ulcer ( P <0.01). And the rate in chronic active gastritis of PHG was significantly higher than that in non active gastritis ( P <0.01) . There were no evidences of Hp infection rate being associated with liver function grading. Conclusion: Although H.pylori infection was related with chronic active gastritis in PHG, it was not the essential pathogenesis factor in PHG. |
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| Keywords: | Liver cirrhosis/etiology Portal hypertensive gastropathy Helicobacter pylori /pathogenicity |
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