| 丹参注射液对麻醉犬血流动力学的影响 |
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| 引用本文： | 周秀梅,杨文彬,柴秋彦,田岳凤. 丹参注射液对麻醉犬血流动力学的影响[J]. 山西中医学院学报, 2004, 5(4): 13-14 |
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| 作者姓名： | 周秀梅 杨文彬 柴秋彦 田岳凤 |
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| 作者单位： | 山西省中医药研究院,山西,太原,030012;山西省医药研究所,山西,太原,030006;山西中医学院,山西,太原,030024 |
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| 基金项目： | 山西省教委资助项目(项目编号:200265) |
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| 摘 要： | 目的:通过观察丹参注射液对麻醉犬血流动力学各项指标的影响,探讨其治疗各种心脑血管疾病的作用机理。方法:采用健康杂种家犬麻醉开胸,用RM-6000型多导生理记录仪及MF-1100电磁血流量计分别测定或计算血流动力学各项指标。结果:丹参注射液在8mg/kg剂量时,可降低舒张压(DAP)和平均动脉压(MAP),并可轻微增加左心室内压最大上升速率(+dp/dtmax)及心输出量(CO)。结论:丹参注射液具有一定的扩张外周血管,降低外周血管阻力,增加心肌收缩力,增加心输出量的作用。
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| 关 键 词： | 丹参注射液 血流动力学 实验研究 |
| 文章编号： | 1671-0258(2004)04-0013-02 |
| 修稿时间： | 2004-09-22 |
Influence of Danshen Injection on Hemodynamics in Anaesthetized Dogs |
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| Zhou Xiumei et al. Influence of Danshen Injection on Hemodynamics in Anaesthetized Dogs[J]. Journal of Shanxi College of Traditional Chinese Medicine, 2004, 5(4): 13-14 |
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| Authors: | Zhou Xiumei et al |
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| Abstract: | Objective:To study the influence of Danshen injection on every index of hemodynamics in anaesthetized dogs and to probe into the mechanism of its treatment for various cardio-cerebral vascular diseases.Methods:Every index of hemodynamics was determined and calculated respectively by using RM-6000 model polygraph physiological recorder and MF-1100 electromagnetic blood flow meter in the anaesthetized open chest dogs.Results:In a dosage of 8mg.kg-1,diastolic pressure and MAP were decreased,maximal ascending rate of left intraventricular pressure(+dp/dtmax)and cardiac out put were increased slightly.Conclution:The functions of this medicine were expansion of periphery blood vessel and reduction its resistance,increase in myocardium contractive force and in cardiac out put. |
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| Keywords: | danshen injection hemodynamics experiment |
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