TREATMENT OF HYPERHIDROSIS WITH TOPICAL METHENAMINE |
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| Authors: | PAUL R. BERCSTRESSER M.D. ROBERTO QUERO M.D. |
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| Affiliation: | From the Department of Dermatology, University of Miami School of Medicine and Dermatology Service, Miami Veterans Administration Hospital, Miami, Florida |
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| Abstract: | ![]()
ABSTRACT: idiopathic palmar and plantar hyperhidrosis is a relatively common disor-der of eccrine sweat gland function. Treat-ment with glufaraldehyde or formaldehyde, although successful, may cause undesirable side effects. Methenamine is a polycyclic organic compound which releases ammonia and formaldehyde at acid pH. Five per cent methenamine in a firm slick gel, applied daily to one palmar or plantar surface of 109 patients with hyperhidrosis, resulted in significantly less sweating after one month. No patients were sensitized to formaldehyde. |
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