| 猫儿刺叶中的三萜皂苷类成分 |
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| 引用本文： | 谢光波,姜勇,雷连娣,屠鹏飞.猫儿刺叶中的三萜皂苷类成分[J].中国天然药物,2009(3):206-209. |
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| 作者姓名： | 谢光波 姜勇 雷连娣 屠鹏飞 |
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| 作者单位： | [1]北京大学药学院天然药物及仿生药物国家重点实验室,北京100083 [2]电子科技大学生命科学与技术学院,成都610054 |
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| 基金项目： | [Foundation Item] This project was supported by grants from National Natural Science Foundation of China （No. 30672608） and Program for Changjiang Scholars and Innovative Team in University （No. 985-2-063-112） |
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| 摘 要： | 目的：研究猫儿刺（Ilex pernyi Franch）叶中的化学成分。方法：运用多种色谱方法进行分离纯化, 采用波谱解析并结合理化性质鉴定化合物结构。结果：分离得到 9 个化合物：2α, 23-二羟基-乌索酸-28-O-β-D-吡喃葡萄糖苷（1）,常春藤皂苷元-3-O-β-D-吡喃葡萄糖基（1→2）-α-L-吡喃阿拉伯糖苷（2）, 常春藤皂苷元-3-O-β-D-吡喃葡萄糖基（1→2）-β-D-吡喃葡萄糖苷 （3）,常春藤皂苷元-3-O-α-L-吡喃鼠李糖基 （1→2）-β-D-吡喃葡萄糖苷（4）, 23-羟基-乌索酸-3-O-β-D-吡喃葡萄糖苷（5）,竹节参苷Ⅳa （6）,23-羟基-乌索酸-3-O-β-D-吡喃葡萄糖醛酸甲酯苷（7）,铁冬青苷XXXVII （8）, 3-O-β-D-吡喃葡萄糖醛酸基-2α, 23-二羟基-乌索酸-28-O-β-D-吡喃葡萄糖苷（9）。结论：9 个化合物均为首次从该植物中分离得到。
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| 关 键 词： | 猫儿刺 冬青科 三萜皂苷 |
Triterpene Saponins from the Leaves of llex pernyi |
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| XIE Guang-Bo,JIANG Yong,LEI Lian-Di,TU Peng-Fei.Triterpene Saponins from the Leaves of llex pernyi[J].Chinese JOurnal of Natural Medicines,2009(3):206-209. |
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| Authors: | XIE Guang-Bo JIANG Yong LEI Lian-Di TU Peng-Fei |
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| Institution: | 1State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Cen- ter, Beijing 100083; 2School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China) |
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| Abstract: | AIM： To study the chemical constituents from the leaves of Ilex pernyi. METHODS： The chemical constituents were isolated by various column chromatographic methods and their structures were identified by spectral data together with physicochemical analysis. RESULTS： Nine known compounds were isolated and identified as 26t, 3β, 23-trihydroxyurs-12-en-28-oic acid β-D-glucopyranosyl ester （1）, hederagenin 3-O-β-D-glucopyranosyl- （1→2）-O-α-L-arabinopyranoside （2）, hederagenin 3-O-β-D-glucopyranosyl-（1→2）-O-β-D-glucopyranoside （3）, heder- agenin 3-O-ot-L-rhamnopyranosyl-（1→2）-O-β-D-glucopyranoside （4）, 3-O-β-D-glucopyranosyl-23-hydroxyursolic acid （5）, chikusetsusaponin Ⅳa （6）, 3β-23-dihydroxy-urs-12-en-28-oic acid 3-O-β-D-glucuronopyranoside 6＇-O-methyl ester （7）, ilexoside XXXVII （8）, 3-O-β-D-glucuronopyranosyl-2α, 3β, 23-trihydroxyurs-12-en-28-oic acid β-D-glucopy- ranosyl ester （9）. CONCLUSION： The nine compounds were isolated from this plant for the first time. |
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| Keywords: | Ilex pernyi Aquifoliaceae Triterpene saponin |
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