| 紫花地丁的化学成分 |
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| 引用本文： | 周海艳,秦民坚,洪俊丽,倪月娟,吴刚.紫花地丁的化学成分[J].中国天然药物,2009(4):290-292. |
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| 作者姓名： | 周海艳 秦民坚 洪俊丽 倪月娟 吴刚 |
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| 作者单位： | [1]中国药科大学中药资源学研究室,南京210038 [2]中国药科大学现代中药教育部重点实验室,南京210038 |
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| 摘 要： | 目的：对紫花地丁（Violayedoensis Makino）的化学成分进行研究。方法：采用色谱法进行化合物的分离纯化,通过波谱数据和理化性质鉴定化合物结构。结果：分离并鉴定出11个化合物,其中6个香豆素类：秦皮乙素（1）、东莨菪素（2）、菊苣苷（3）、早开堇菜苷（4）、秦皮甲素（5）、双七叶内酯（6）;3个黄酮类：槲皮素-3-O-β-D-葡萄糖苷（7）、山柰酚-3-O-β-D-葡萄糖苷（8）、芹菜素（9）;2个甾醇类：β-谷甾醇（10）、胡萝卜苷（11）。结论：秦皮甲素、胡萝卜苷为首次从堇菜属植物中分得;槲皮素-3-O-β-D-葡萄糖苷、山柰酚-3-O-β-D-葡萄糖苷、菊苣苷、早开堇菜苷、芹菜素均为首次从紫花地丁中分得。
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| 关 键 词： | 紫花地丁 堇菜科 化学成分 香豆素 |
Chemical Constituents of Viola yedoensis |
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| ZHOU Hai-Yan,QIN Min-Jian,HONG Jun-Li,NI Yue-Juan,WU Gang.Chemical Constituents of Viola yedoensis[J].Chinese JOurnal of Natural Medicines,2009(4):290-292. |
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| Authors: | ZHOU Hai-Yan QIN Min-Jian HONG Jun-Li NI Yue-Juan WU Gang |
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| Institution: | 1Department of Resources Science of Traditional Chinese Medicines;2Key Laboratory of Modern Chinese Medicines (Ministry of Education), China Pharmaceutical University, Nanjing 210038, China) |
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| Abstract: | AIM： To study the chemical constituents of Viola yedoensis, and its active components. METHODS： The Compounds were isolated and purified by chromatography and their structures were identified by spectral data and other methods. RESULTS： Eleven compounds were isolated and identified as aesculetin （1）, scopoletin （2）, cichoriin （3）, prionanthoside （4）, esculin （5）, euphorbetin （6）, quercetin-3-O-β-D-glucoside （7）, kaempferol-3-O-β-D- glucoside （8）, apigenin （9）, β-sitosterol （10）, daucosterol （11）. CONCLUSION： esculin, and daucosterol were obtained from Viola for the first time, and quercetin-3-O-β-D-glucoside, kaempferol-3-O-β-D-glucoside, cichoriin, prionanthoside, apigenin were firstly isolated from Viola yedoensis. |
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| Keywords: | Viola yedoensis Violaceae Chemical constituents Coumarin |
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