| 电针对大鼠下丘脑孤啡肽表达的影响 |
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| 引用本文： | 陈海萍,高慧,陈伯英.电针对大鼠下丘脑孤啡肽表达的影响[J].上海针灸杂志,2003,22(11):7-10. |
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| 作者姓名： | 陈海萍 高慧 陈伯英 |
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| 作者单位： | 复旦大学上海医学院中西医结合系,神经生物学国家重点实验室,上海,200032 |
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| 摘 要： | 目的 研究电针对大鼠下丘脑孤啡肽表达的影响。方法 应用免疫组化ABC法观察大鼠下丘脑孤啡肽变化；应用RT-PCR技术观察大鼠孤啡肽前体mRNA的变化。结果 电针可以上调去卵巢大鼠下丘脑孤啡肽免疫阳性细胞数，去卵巢大鼠下丘脑孤啡肽前体mRNA含量在电针前后变化不大。结论 电针可以影响去卵巢大鼠下丘脑孤啡肽表达。
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| 关 键 词： | 电针 大鼠 下丘脑 孤啡肽 表达 |
| 文章编号： | 1005-0957(2003)11-0007-04 |
Effects of Electroacupuncture on the Expression of Hypothalamic OFQ in Ovariectomized Rat |
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| CHEN Hai ping,GAO Hui,CHEN Bo ying.Effects of Electroacupuncture on the Expression of Hypothalamic OFQ in Ovariectomized Rat[J].Shanghai Journal of Acupuncture and Moxibustion,2003,22(11):7-10. |
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| Authors: | CHEN Hai ping GAO Hui CHEN Bo ying |
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| Institution: | CHEN Hai ping,GAO Hui,CHEN Bo ying. Department of Integrated Chinese and Western Medicine,Shanghai Medical Center,Fudan Uuniversity, the Key State Laboratory of Medical Neurobiology,Shanghai 200032,China |
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| Abstract: | Objective To explore the effects of electroacupuncture on the expression of hypothalamic OFQ in the ovariectomized rat. Methods Immunohistochemistry technology, RT PCR and Image Processing were used. Results EA could improve OFQ immunoreactivity in hypothalamus of the ovariectomized rat, while EA made no influence on the exprssion of Prepronociceptin mRNA in the ovariectomized rat. Conclusion Electroacupuncture might influence on the expression of hypothalamic OFQ in the ovariectomized rat. |
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