在不同年龄中结肠癌患者的临床和内镜分析

目的　探讨不同年龄人结肠癌的临床特点。方法　对经结肠镜检查的 2 17例结肠癌患者按年龄分为三组 ,老年组 (>6 0岁 )、中年组 (36～ 5 9岁 )、青年组 (<35岁 )。比较不同年龄组结肠癌患者的临床表现、内镜下表现、病理及雌激素受体表达等肿瘤特征进行分析并与中青年组患者相对照。结果　老年组粘液血便为主占 90 2 % ,肿瘤分布以直肠和乙状结肠多见 ,显著高于青年组。老年男性雌激素受体 (ER)阳性率显著降低。结论　本研究表明老年人结肠癌患病率高、结肠癌发病高峰为 6 0～ 70岁。老年人结肠癌发生部位以左半结肠多见 ,分化好 ,病程长。

Clinical and endoscopic analysis of large bowel cancer of elderly people

Objective This study was designed to understand the characteristics of colon cancer in aged people. Methods A total of 217 patients with colon cancer diagnosed by endoscopy were categorized after age into aged(>60years), mid-aged(36-59years),and young(<35years)groups. According to colon cancer of aged people, clinical endoscopic and pathologic features as well as histchemical receptors were analysis and were compared with young patients. Results Colon cancer appeared most frequently with bloody stools as chief complaint(90.2%) in the aged groups. The colon cancer in elderly people usually occur in rectum and sigmoid colon, being significantly higher than that in the young group. estrogen receptors were less commonly seen in the aged. Conclusion In the elderly patients with colon cancer was significantly higher, Incidence peak of colon cancer in this series occurred at 60-70 years of age. The elderly patients were affected most often by left by left colon tumor with high differentiation and slow progression.