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Severe acute respiratory syndrome, Beijing, 2003
Authors:Liang Wannian  Zhu Zonghan  Guo Jiyong  Liu Zejun  Zhou Weigong  Chin Daniel P  Schuchat Anne;Beijing Joint SARS Expert Group
Institution:Beijing Municipal Health Bureau and Beijing Municipal Centers for Disease Prevention and Control, Beijing, China.
Abstract:The largest outbreak of severe acute respiratory syndrome (SARS) struck Beijing in spring 2003. Multiple importations of SARS to Beijing initiated transmission in several healthcare facilities. Beijing's outbreak began March 5; by late April, daily hospital admissions for SARS exceeded 100 for several days; 2,521 cases of probable SARS occurred. Attack rates were highest in those 20-39 years of age; 1% of cases occurred in children <10 years. The case-fatality rate was highest among patients >65 years (27.7% vs. 4.8% for those 20-64 years, p < 0.001). Healthcare workers accounted for 16% of probable cases. The proportion of case-patients without known contact to a SARS patient increased significantly in May. Implementation of early detection, isolation, contact tracing, quarantine, triage of case-patients to designated SARS hospitals, and community mobilization ended the outbreak.
Keywords:severe acute respiratory syndrome  disease outbreaks  epidemiology  China  nosocomial infection  SARS virus  disease transmission
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