Severe acute respiratory syndrome, Beijing, 2003 |
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Authors: | Liang Wannian Zhu Zonghan Guo Jiyong Liu Zejun Zhou Weigong Chin Daniel P Schuchat Anne;Beijing Joint SARS Expert Group |
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Institution: | Beijing Municipal Health Bureau and Beijing Municipal Centers for Disease Prevention and Control, Beijing, China. |
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Abstract: | The largest outbreak of severe acute respiratory syndrome (SARS) struck Beijing in spring 2003. Multiple importations of SARS to Beijing initiated transmission in several healthcare facilities. Beijing's outbreak began March 5; by late April, daily hospital admissions for SARS exceeded 100 for several days; 2,521 cases of probable SARS occurred. Attack rates were highest in those 20-39 years of age; 1% of cases occurred in children <10 years. The case-fatality rate was highest among patients >65 years (27.7% vs. 4.8% for those 20-64 years, p < 0.001). Healthcare workers accounted for 16% of probable cases. The proportion of case-patients without known contact to a SARS patient increased significantly in May. Implementation of early detection, isolation, contact tracing, quarantine, triage of case-patients to designated SARS hospitals, and community mobilization ended the outbreak. |
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Keywords: | severe acute respiratory syndrome disease outbreaks epidemiology China nosocomial infection SARS virus disease transmission |
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