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| Effects of low-intensity pulsed ultrasound in repairing injured articular cartilage | |
| 引用本文： | 贾小林,陈文直,周昆,王智彪. Effects of low-intensity pulsed ultrasound in repairing injured articular cartilage[J]. 中华创伤杂志(英文版), 2005, 8(3): 175-178 |
| 作者姓名： | 贾小林 陈文直 周昆 王智彪 |
| 作者单位： | Institute of Ultrasonic Engineering in Medicine，Chongqing University of Medical Sciences，Chongqing 400016，China，Institute of Ultrasonic Engineering in Medicine，Chongqing University of Medical Sciences，Chongqing 400016，China，Institute of Ultrasonic Engineering in Medicine，Chongqing University of Medical Sciences，Chongqing 400016，China，Institute of Ultrasonic Engineering in Medicine，Chongqing University of Medical Sciences，Chongqing 400016，China |
| 基金项目： | TheprojectwasfundedbytheNationalNaturalScience FoundationofChina(No.39630340). |
| 摘 要： | Articularcartilageisakindofavascularmusculoskeletaltissueswitharelativelylowcapacityforintrinsicrepairorregeneration.Intheabsenceofavailablestemcells,thereislittlehopeforcartilagerepairafterinjuryandthetissuesprogress alongadegenerativepathwaythatdestroysthe biochemicalandbiomechanicalproperties.Sorepairof damagedarticularcartilageisoneofthemostdifficult problemsinorthopaedicsandnosatisfactorytreatment methodhasbeenfoundinthisfield.Ultrasoundhas beenwidelyusedinclinicaldiagnosisandtreatment.It… |
| 关 键 词： | 关节软骨损伤 低脉冲治疗 超频率音响 治疗方法 |
Effects of low-intensity pulsed ultrasound in repairing injured articular cartilage |
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| JIA Xiao-lin,CHEN Wen-zhi,Zhou Kun,WANG Zhi-Biao. Effects of low-intensity pulsed ultrasound in repairing injured articular cartilage[J]. Chinese journal of traumatology, 2005, 8(3): 175-178 | |
| Authors: | JIA Xiao-lin CHEN Wen-zhi Zhou Kun WANG Zhi-Biao |
| Affiliation: | Institute of Ultrasonic Engineering in Medicine, Chongqing University of Medical Sciences, Chongqing 400016, China |
| Abstract: | Objective: To investigate the effects of low-intensity pulsed ultrasound in repairing injured articular cartilage. Methods: Ten adult New Zealand rabbits with bilateral full-thickness osteochondral defects on the cartilage surface of intercondylar fossas were used in this study. The wounds in the left knees were treated with low-intensity pulsed ultrasound as the experimental group. The right knees received no treatment as the control group. All the animals were killed at 8 weeks after injury and the tissues in the wounds were collected for gross appearance grading, histological grading and proteoglycan quantity. Results: The scores of the gross appearance grades, histological grades and the optical density of toluidine blue of the tissues in the experimental group were significantly higher than those of the controls at 8 weeks after injury (P<(0.05)). Conclusions: Low-intensity pulsed ultrasound can accelerate the repair of injured articular cartilage. |
| Keywords: | Cartilage Wounds and injuries Rabbits Low-intensity pulsed ultrasound |
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