儿童过敏性紫癜60例临床分析

目的 分析过敏性紫癜(HSP)患儿的临床资料,总结该病的临床特征.方法 对60例HSP患儿临床表现进行总结分析.结果 (1)发病年龄在3～14岁,多见于5～10岁,女性多于男性(比率为2:1),冬春季好发;以呼吸道感染为主要诱因.(2)所有患儿均有典型皮肤紫癜,累及双下肢(100%),其次是臀部(30%)、双上肢(13%)、颜面(7%);80%以皮肤紫癜为首发症状,30%皮肤紫癜于病程中反复出现;少数以胃肠道及关节症状首发.(3)60%患儿关节受累;胃肠道症状发生率47%;肾损害发生率13%.结论 HSP皮肤紫癜的发生率100%,关节症状和胃肠症状在大多患儿均可发现,紫癜性肾炎(HSPN)是其严重的并发症,肾脏受损程度直接影响HSP患儿的预后.

Clinical diagnosis and treatment of 60 children with henoch-schonlein purpura

Objective To analyze the clinical data of henoch-schonlein purpura(HSP)in children and to conclude the clinieal featrues of HSP.Methods The clinieal features of 60 children with HSP were analyzed.Results(1)The age of onset of all the 60 children with HSP was from 3 to 14 yearn old,especially from 5 to 10 years and the female patients were more than the male patients(the ratewas 2:1).Of the 60 children,they developed HSP in the four seasons,especially in the spring and winter;most of the HSP patients revealed evident predisposing factors,mainly upper respiratory infection.(2)All the patients had typical purpura.80% had typical purpura as the presenting contancous sign.The distribution of rash in the lower extremitiees,buttock upper extremities and face was 100%,30%,13% and 7%.30% occurre,repeatedly.(3)Gastrointestinal involvement and arthritis occurred rate is 47% and 60%,respectively.Of all the patients,13% devdoped HSP nephritis manifested as isolated hematuria and/or protcinuria.Conclusion HSP has its own clinical and episodic features.It is not difficult to diagnose the typical case.HSPN is its serious syndrome,it should be long-term foflow-up of kidney conditions.