Use of cyst fluid CEA, CA19-9, and amylase for evaluation of pancreatic lesions期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Use of cyst fluid CEA, CA19-9, and amylase for evaluation of pancreatic lesions

Authors:	Christine L.H. Snozek Ranjan C. Mascarenhas Dennis J. O'Kane

Affiliation:	^a Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA ^b Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA

Abstract:	Objectives The study goals were development of reference intervals and an interpretive algorithm for pancreatic cyst fluid tumor markers. Design and methods 442 pancreatic cyst fluids were tested for CEA, CA19-9, and amylase. Results CEA > 30 ng/mL discriminates mucinous from non-mucinous cysts. After CEA analysis, amylase and CA19-9 segregate non-mucinous and mucinous subtypes, respectively. Conclusions Pancreatic cyst fluid tumor markers supplement other diagnostic measures. This study provides estimated reference intervals and an algorithm for interpretation.

Keywords:	Pancreatic cancer Tumor markers Mucinous cysts Carcinoembryonic antigen Amylase
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