甘精胰岛素联合瑞格列奈治疗2型糖尿病临床疗效观察

目的：研究并分析甘精胰岛素联合瑞格列奈治疗2型糖尿病的临床疗效。方法：选择本院收治的60例2型糖尿病患者为研究对象，分为观察组与对照组，观察组使用甘精胰岛素联合瑞格列奈进行治疗，对照组皮下注射预混胰岛素，观察两组患者治疗前后空腹血糖（FPG）、餐后2 h血糖（2 h PG）、糖化血红蛋白（HbAlc）的变化情况，比较两组治疗有效率。结果：观察组与对照组治疗后FPG、2 h PG、HbAlc均显著降低，观察组治疗效果更加显著，组间比较差异均有统计学意义（P＆lt;0.05）。结论：甘精胰岛素联合瑞格列奈对于2型糖尿病患者能够达到良好的降糖效果，可以改善胰岛素的敏感性，该种治疗方式值得在临床中进行推广和使用。

The Clinical Analysis of Insulin Glargine Combined with Repaglinide in Treatment of Type 2 Diabetes

Objective：To discuss the clinical efficacy and value of insulin glargine combined with repaglinide in treatment of type 2 diabetes. Method：60 patients with type 2 diabetic patients were randomly divided into observation group and control group,the observation group was treated with subcutaneous injection of insulin glargine combined with the oral treatment of repaglinide,the control group was treated with subcutaneous injection therapy of premixed insulin,FPG,2 h PG,HbAlc levels,the amount of insulin and hypoglycemia rates in two groups were observed. Result：FPG, 2 h PG,HbA1c levels in two groups after treatment were significantly lower than before treatment（P＆lt;0.05）,the incidence of hypoglycemia in the observation group during treatment was significantly lower than that in the control group（P＆lt;0.05）.Conclusion：Glargine insulin plus repaglinide can reduce the incidence of low blood sugar while maintaining stable blood glucose and reduce the amount of insulin,which is a better option in the treatment of type 2 diabetes and worthy of clinical application.