阴茎疣状癌误诊分析

目的探讨阴茎鳞状细胞癌的特殊类型疣状癌误诊的原因和治疗方法。方法回顾分析9例阴茎疣状癌患者的诊治资料,患者平均年龄49岁,肿瘤呈菜花样生长。瘤体病现活检6例误诊。4例患者肿瘤局限于阴茎头者行肿瘤局部切除术,其余5例均行阴茎部分切除术。结果病理检查见肿瘤细胞分化良好,手术标本切缘未见肿瘤细胞。病理诊断均为“高分化鳞状细胞癌”。随访2-6年,平均3．8年,无1例肿瘤复发或转移。结论阴茎疣状癌细胞分化好,组织活检易误诊。由于其生物学行为以局部侵袭性生长为主,手术治疗预后好。

Analysis of misdiagnosis of penile verrucous carcinoma

Objective To study the misdiagnosis and treatment of penile verrucous carcinoma, a distinctive variant of squamous cell carcinoma. Methods The clinical date of 9 patients with penile verrucous carcinoma were analyzed retrospectively; mean age, 49 years. The tumors showed exophytic. The misdiagnosis was established by biopsy of the lesion for 6 patients. The tumors located at glans in 4 patients were treated by local excision, while the other 5 patients underwent partial penectomy. Results Histopathologic examination of the specimens confirmed tumors-free surgical margins in all the cases. The tumor cell were mostly well-differentiated. Histopathologic diagnosis was "Well-differentiated (Grade) Squamous Carciinoma". All patients were followed up for an average of 3.8 years (2-6years), showed no recurrence and metastasis. Conclusion The tumor cells of penile verrucous carcinoma were mostly well-differentiated and the misdiagnosis is established by inadequate biopsy of the lesion. This carcinoma is characterized by slow growth and locally aggressive nature, the prognosis is favorable after surgical operation treatment.