不同透析频率对维持性血液透析患者感染的影响

目的 研究不同透析频率对维持性血液透析患者感染、转归的影响.方法 根据透析频率将53例慢性肾衰竭维持性血液透析患者分为三组:A组19例,每周透析3次;B组15例,每周透析2次;C组19例,每2周透析3次.记录透析1年内三组感染发生情况及死亡例数.结果 三组共发生感染62例次,A组17例次,B组18例次,C组27例次;感染部位依次为肺部35例次(56.45%)、血管通路14例次(22.58%)、尿路8例次(12.90%)和消化道5例次(8.06%).三组共死亡8例,病死率15.09%(8/53).A组死亡1例,B组死亡1例,C组死亡6例.三组预后比较差异有统计学意义(χ2=6.293,P<0.05).结论 透析频率低于2次/周的患者感染发生率高,病死率也高.应调整透析方案,增加透析频率.

Influence of different dialysis frequence on infection of maintenance hemodialysis patients

Objective To study the influence of different dialysis frequence on infection and prognosis of maintenance hemedialysis patients. Methods Fifty-three maintenance hemodialysis patients with chronic kidney disease were divided into 3 groups. Groups A, B, C dialysed thrice per week (19 cases),twice per week (15 cases) and thrice per two weeks (19 cases), respectively. All the patients were dialysed for 1 year. The rate of infection, death number and death reason were recorded. Results All the cases were infected 62 times (17 times in group A, 18 times in group B and 27 times in group C). Pulmonary infection,blood vessels infection, urinary tract infection and digestive tract infection happened 35 times(56.45% ), 14 times (22.58%), 8 times (12.90%) and 5 times (8.06%) respectively. Eight cases died in three groups,and the total death rate was 15.09%, with 1 case in group A,1 case in group B and 6 cases in group C.There was significant difference in prognosis among three groups (χ2 =6.293,P <0.05). Conclusions Patients who dialysis less than twice per week have higher rate of infection and death. Dialysis program should be adjusted and dialysis frequence should be increased.