The production of a human monoclonal antibody defining a split of HLA-DRw13 (DRw13b) |
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| Authors: | M. Bunce P. M. Sutton A. Ting P. J. Morris. M. Bunce |
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| Affiliation: | Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, U.K. |
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| Abstract: | ![]()
By use of the heterohybridoma technique we have produced a human monoclonal antibody (NDS40) which detects a split of HLA-DRw13 (DRw13b) which is in linkage with HLA-DQw1. In addition, the antibody reacts with cells positive for HLA-DRw8 and DRw11, but does not react with the commonly found split of DRw13 (DRw13a) which is associated with DQw1. NDS40 is cytotoxic and is of the lambda IgM class. |
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