| 阿立哌唑与氯氮平治疗首发精神分裂症对照研究 |
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| 引用本文： | 陈静,周燕,查显友.阿立哌唑与氯氮平治疗首发精神分裂症对照研究[J].山东精神医学,2007,20(2):97-98. |
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| 作者姓名： | 陈静 周燕 查显友 |
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| 作者单位： | 浙江省嘉兴市康慈医院，浙江省嘉兴市康慈医院，浙江省嘉兴市康慈医院 |
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| 摘 要： | 目的比较阿立哌唑与氯氮平治疗首发精神分裂症的疗效及安全性。方法将63例首发精神分裂症患者随机分为阿立哌唑组(n=32)和氯氮平组(n=31)进行治疗,疗程8周。采用PANSS量表和TESS量表评定疗效和不良反应。结果两组疗效差异无显著性(P>0.05),阿立哌唑不良反应显著少于氯氮平(P<0.01)。结论阿立哌唑与氯氮平治疗首发精神分裂症均有效,前者不良反应少,安全性高。
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| 关 键 词： | 精神分裂症 阿立哌唑 氯氮平 |
| 文章编号： | 1009-7201（2007）-02-0097-02 |
| 收稿时间： | 2006-11-15 |
| 修稿时间： | 2006-11-152007-01-24 |
A comparative study of aripiprazole and clozapine in the treatment of first-episode schizophrenia |
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| CHEN Jing,ZHOU Yan,ZHA Xian-you.A comparative study of aripiprazole and clozapine in the treatment of first-episode schizophrenia[J].Shangdong Archives of Psychiatry,2007,20(2):97-98. |
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| Authors: | CHEN Jing ZHOU Yan ZHA Xian-you |
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| Institution: | The Kangci Hospital of Jiaxing City , Zhejiang 314501,China |
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| Abstract: | Objective To compare the efficacy and safety of aripiprazole in the treatment of first-episode schizophrenia. Methods A total of 63 patients with first-episode schizophrenia were randomly divided into aripiprazole group and clozapine group for 8 weeks of treatment . The efficacy and side effects were assessed Positive and Negative symptom Scale (PANSS) and Treatment Emergent Symptom Scale (TESS).Rusults There was no significant difference in efficacy between two groups. Aripiprazole group had fewer side effects than clozapine group.Conclusion Aripiprazole and clozapine are effective in the treatment of first-episode schizophrenia .Aripiprazole has fewer side effects. |
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| Keywords: | Schizophrenia Aripiprazole Clozapine |
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