FDG PET/CT对骨及软组织肿瘤诊断和疗效评价的应用

目的 探讨FDG PET/CT显像诊断骨或软组织肿瘤和术后疗效评价的价值.方法 回顾性分析48例已证实的骨及软组织肿瘤患者的FDG PET/CT显像结果,以鉴别诊断肿瘤的良恶性,是否复发、有无其他转移及周围侵犯,并与同机CT对比分析.结果 FDG PET/CT显像诊断骨及软组织肿瘤灵敏度为100%(7/7),特异性为80%(4/5);监测术后复发(残留)的灵敏度和特异性均为100%;通过PET/CT显像多发现转移灶35处,对于肺部12个转移灶,有赖于同机CT.结论 FDG PET/CT显像对骨及软组织肿瘤的诊断优于常规影像检查,可早期准确判断肿瘤复发,同时发现更多转移灶(肺转移除外),对肿瘤治疗诊断有指导作用.

FDG PET/CT imaging in the diagnosis and efficacy evaluation for bone and soft tissue tumors

Objective To assess the clinical value of FDG PET/CT imaging in the diagnosis and efficacy evaluation for bone and soft tissue tumors. Methods The FDG PET/CT images of 48 patients diagnosed with bone and soft tissue tumors were retrospectively analyzed. These FDG PET/CT images were analyzed in order to differentially diagnose the tumors to be benign or malignant, and to confirm whether there was recurrence, distal metastasis and surrounding invasion or not. Besides, comparative analysis was done between the FDG PET/CT imaging and the CT imaging. Results For FDG PET/CT imaging in the diagnosis for bone and soft tissue tumors, the rate of sensitivity was 100% （7/7）, and the rate of specificity was 80% （4/5）. According to the monitoring results of recurrence and residual, both the post-operative rate of sensitivity and the post-operative rate of specificity were 100%. Extra 35 metastases were detected by the PET/CT imaging, and the other 12 pulmonary metastases were found by the CT imaging. Conclusions FDG PET/CT imaging in the diagnosis for bone and soft tissue tumors is better than the routine imaging. It can accurately detect the recurrence of tumors in the early stage, and find extra metastasis （except pulmonary metastasis）. Therefore, it can assist the treatment and diagnosis against tumors.