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| 灵益胶囊控制阿片类戒断症状的临床疗效评价 | |
| 引用本文： | 李静,黄明生,万文鹏,田维才,刘闯,陈小蓉,张波,杨芳,刘波,王应龙.灵益胶囊控制阿片类戒断症状的临床疗效评价[J].华西医学,1999,14(1):18-21. |
| 作者姓名： | 李静 黄明生 万文鹏 田维才 刘闯 陈小蓉 张波 杨芳 刘波 王应龙 |
| 作者单位： | 1. 华西医科大学附属第一医院精神科 2. 云南省药物依赖防治研究所,650000 3. 湖北省沙市复员退伍军人精神病医院,434000 |
| 摘 要： | 中药灵益胶囊是用于控制阿片类药物依赖戒断症状的复方中药制剂，已被卫生部批准进行临床试验，本研究采用随机双盲和开放多中心临床，共完成３３０例洛洛因依赖者的脱毒效应评定。 |
| 关 键 词： | 灵益胶囊 阿片类戒断症状 临床疗效 不良反应 |
Clinical Trial of Ningyi Capsule in Treatment of Opioid Withdrawal Syndrome |
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| LI Jing ,HUANG Ming-sheng ,WAN Wen peng ,et al Institute of Mental Health,The First Hospital Affiliated to West China University of Medical Sciences,Chengdu Yunnan Institute for Drug Abuse.Clinical Trial of Ningyi Capsule in Treatment of Opioid Withdrawal Syndrome[J].West China Medical Journal,1999,14(1):18-21. | |
| Authors: | LI Jing HUANG Ming-sheng WAN Wen peng et al Institute of Mental Health The First Hospital Affiliated to West China University of Medical Sciences Chengdu Yunnan Institute for Drug Abuse |
| Institution: | LI Jing 1,HUANG Ming-sheng 1,WAN Wen peng 2,et al 1 Institute of Mental Health,The First Hospital Affiliated to West China University of Medical Sciences,Chengdu 610041 2 Yunnan Institute for Drug Abuse,650000 |
| Abstract: | Ningyi capsule is a compound Chinese traditional medicine in treatment of opioid withdrawal syndrome.The efficacy and safety of Ningyi capsule has been compared with Clonidine and Placebo in 330 cases of heroin addicts though multi-center clinical trial(random controlled,double-blinded and open trial).The result showed that the prominence improvement rate of Ningyi capsule was 71 43%,while Clonidine was 58 47%( P >0 05),Placebo was 10 53%( P <0 05).The side effect of Ningyi capsule was lighter than Clonidine( P <0 05).The result of open trial was similar to that of doubleblinded trial.The primary conclusion is that both Ningyi capsule and Clonidine was effective in the treatment of opioid withdrawal syndrome,but Ningyi capsule showed lighter side effect than Clonidine. |
| Keywords: | Ningyi capsule opioid withdrawal syndrome efficacy side effect |
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