| 藿香正气滴丸对正常及乙酰胆碱刺激下动物胃肠道功能的影响 |
| |
| 引用本文： | 温克,焦建杰,刘印忠,高建华,张才丽,娄建石.藿香正气滴丸对正常及乙酰胆碱刺激下动物胃肠道功能的影响[J].中国新药杂志,2011(7). |
| |
| 作者姓名： | 温克 焦建杰 刘印忠 高建华 张才丽 娄建石 |
| |
| 作者单位： | 天津医科大学药理学教研室; |
| |
| 基金项目： | 天津市科技创新专项基金和科技支撑计划重大项目(08FDZDSH01402) |
| |
| 摘 要： | 目的:观察藿香正气滴丸对正常及乙酰胆碱刺激下动物胃肠功能的影响。方法:观察藿香正气滴丸对正常小鼠胃排空和肠推进运动、乙酰胆碱所致大鼠离体胃底条平滑肌收缩、家兔离体肠平滑肌收缩作用以及家兔在体肠平滑肌收缩作用的影响。结果:藿香正气滴丸对正常状态胃肠运动无明显影响;可不同程度抑制乙酰胆碱引起的家兔在体回肠平滑肌收缩幅度以及乙酰胆碱所致大鼠离体胃底平滑肌以及家兔离体十二指肠平滑肌的收缩。结论:藿香正气滴丸对不同状态的胃肠道具有不同影响,对过度兴奋的胃肠道平滑肌收缩具有抑制作用,而对正常状态的胃肠道无明显影响。
|
| 关 键 词： | 藿香正气滴丸 胃排空 肠推进 胃底条 肠平滑肌 |
Effects of Huoxiang Zhengqi dripping pills on normal or ACh-stimulated gastrointestinal functions in animals |
| |
| WEN Ke,JIAO Jian-jie,LIU Yin-zhong,GAO Jian-hua,ZHANG Cai-li,LOU Jian-shi.Effects of Huoxiang Zhengqi dripping pills on normal or ACh-stimulated gastrointestinal functions in animals[J].Chinese Journal of New Drugs,2011(7). |
| |
| Authors: | WEN Ke JIAO Jian-jie LIU Yin-zhong GAO Jian-hua ZHANG Cai-li LOU Jian-shi |
| |
| Institution: | WEN Ke,JIAO Jian-jie,LIU Yin-zhong,GAO Jian-hua,ZHANG Cai-li,LOU Jian-shi(Department of Pharmacology,Tianjin Medical University,Tianjin 300070,China) |
| |
| Abstract: | Objective: To observe the effects of Huoxiang Zhengqi dripping pills(HZDP) on normal or acetylcholine(ACh)-stimulated gastrointestinal functions in animals.Methods: The effects of HZDP on gastric emptying and intestinal propelling in mice,ACh-induced contraction of isolated strips from rat gastric fundus,contraction of rabbit intestinal smooth muscles in vivo or in vitro were observed.Results: HZDP did not affect the functions of gastrointestinal tracts under normal condition.However,it decreased the amplit... |
| |
| Keywords: | Huoxiang Zhengqi dripping pills gastric emptying intestinal propelling gastric fundus strip intestinal smooth muscle |
| 本文献已被 CNKI 等数据库收录！ |
|
