| n-3多不饱和脂肪酸类药物在心血管疾病中的临床应用进展 |
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| 引用本文： | 汪芳.n-3多不饱和脂肪酸类药物在心血管疾病中的临床应用进展[J].中国新药杂志,2011(15). |
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| 作者姓名： | 汪芳 |
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| 作者单位： | 卫生部北京医院心内科; |
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| 摘 要： | 许多临床试验表明n-3多不饱和脂肪酸(n-3 PUFAs)对于冠心病、血脂异常和心力衰竭等人群均具有保护作用,而且已有建议推荐心肌梗死后患者和高甘油三酯血症人群口服此类提纯药物。但在应用过程中,仍有一些值得临床关注的问题,如药物安全性、药物成分和用量等。笔者认为,随着对n-3 PUFAs药物的深入研究,其将有更广阔的应用前景。
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| 关 键 词： | n-3多不饱和脂肪酸 心血管保护作用 临床应用 |
Current advance in clinical application of n-3 polyunsaturated fatty acid drugs in cardiovascular diseases |
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| WANG Fang.Current advance in clinical application of n-3 polyunsaturated fatty acid drugs in cardiovascular diseases[J].Chinese Journal of New Drugs,2011(15). |
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| Authors: | WANG Fang |
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| Institution: | WANG Fang(Department of Cardiology,Beijing Hospital of the Ministry of Health,Beijing 100730,China) |
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| Abstract: | Many clinical trials showed that n-3 polyunsaturated fatty acids(n-3 PUFAs) have protective effects for patients with coronary heart disease,dyslipidemia and heart failure.And n-3 PUFAs are recommended for secondary prevention in patients after myocardial infarction and for the treatment of hypertriglyceridaemia.However,there are some concerns in their clinical application,such as drug safety,compositions,dosages and so on.With further research,n-3 PUFA drugs will have broader prospects for development. |
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| Keywords: | n-3 polyunsaturated fatty acids cardiovascular protective effect clinical application |
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