心理社会干预对乳腺癌患者生存质量影响的对照研究

目的 采用前瞻性随机对照研究,以乳腺癌术后化疗患者为研究对象,探讨心理社会干预对其生存质量的影响.方法 120例病人被随机分配到干预组(60例)和对照组(60例),干预组除常规药物治疗外,接受系统的心理社会干预,如健康教育、放松训练及集体心理干预,对照组只有药物治疗.采用中国癌症化疗患者生活质量量表(QLQ-CCC)及症状自评量表(SCL-90)作为乳腺癌化疗患者生存质量和心理状况的测查指标.结果 乳腺癌化疗患者的生存质量状况以化疗中最差,而治疗结束后,干预组患者的SCL-90总分(131.9士13.7)与对照组(192.5士15.4)相比,P＜0.01;而躯体、心理、社会、总体方面评分分别为:26.7士2.6 分、13.7士1.5 分、8.5士0.8 分、46.9士3.5 分,P＜0.05或0.01,表明干预组患者的不良情绪明显改善,生存质量明显提高.结合对乳腺癌术后化疗患者实施系统的心理社会干预,是改善不良情绪,提高生存质量的有效方法之一,值得推广应用.

The Effect of Psycho-social Intervention on Quality of Life in Breast Cancer Chemotherapy Patients

Objective To explore the quality of life in breast cancer chemotherapy patients after psychological social intervention.Methods 120 patients were randomly divided into intervention group(60 cases) and control group(60 cases).Besides medicines treatment,and the intervention group also receives systematic psycho-social intervention,Such as health education,relaxation training and collective psychological intervention,while the control group only keep treatment with drug.Quality of life in patients with breast cancer and mental conditions were tested by QLQ-CCC and SCL-90.Results The status of QOL in during-therapy patients was the worst.After psychological intervention,compared to the control group,the patients' SCL-90,QLQ-CCC were changed towards better,but only spiritual/psychological domain were changed towards better in during-therapy patients.Conclusion Timely systematic psycho-social intervention to the breast cancer chemotherapy patients is an effective method for their QOL and worth spread application.