| MVP方案加或不加光量子血液疗法治疗晚期非小细胞肺癌 |
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| 引用本文： | 胡永军,刘爱琴,陈凤军,陈素华.MVP方案加或不加光量子血液疗法治疗晚期非小细胞肺癌[J].临床肿瘤学杂志,2004,9(3):253-255,257. |
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| 作者姓名： | 胡永军 刘爱琴 陈凤军 陈素华 |
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| 作者单位： | 1. 255120,山东淄博,淄博矿务局中心医院肿瘤内科
2. 北京军区总医院肿瘤内科 |
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| 摘 要： | 目的 :观察MVP方案加光量子血液疗法治疗晚期非小细胞肺癌 (NSCLC)的近期疗效和毒副作用。方法 :将 4 8例晚期NSCLC患者随机分为治疗组和对照组 ,分别接受MVP方案 (丝裂霉素、西艾克、顺铂 )及化疗当日开始光量子血液治疗法或单纯MVP方案化疗。结果 :治疗组部分缓解率 5 4 2 % ,对照组 2 5 0 % (P <0 0 5 ) ,中位缓解期分别为 5 1个月及 4 2个月。治疗组毒性明显小于对照组。结论 :MVP方案化疗同时应用光量子血液疗法治疗晚期NSCLC ,疗效有所提高 ,毒性有所减少。
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| 关 键 词： | MVP方案 光量子血液疗法 治疗 晚期非小细胞肺癌 毒副作用 丝裂霉素 西艾克 顺铂 |
| 文章编号： | 1009-0460(2004)03-0253-0 |
MVP Regimen with or without Photohemotherapy in Treatment of Advanced Non-small Cell Lung Cancer |
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| HU Yong-jun,LIU Ai-qing,CHEN Feng-jun,et al..MVP Regimen with or without Photohemotherapy in Treatment of Advanced Non-small Cell Lung Cancer[J].Chinese Clinical Oncology,2004,9(3):253-255,257. |
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| Authors: | HU Yong-jun LIU Ai-qing CHEN Feng-jun |
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| Institution: | HU Yong-jun,LIU Ai-qing,CHEN Feng-jun,et al. Department of Oncology,Zibo Coal Mining Central Hospital,Zibo 255120 |
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| Abstract: | Objective:To observe the response rate and toxicity of MVP regimen with or without photohemotherapy in the treatment of advanced non-small cell lung cancer (NSCLC).Methods:Forty-eight patients with advanced NSCLC were randomly divided into treatment group and control group receiving MVP regimen (mitomycin c, Vindesine, cisplatin) plus photohemotherapy or MVP regimen alone respectively.Results:The partial response rate was 54.2% in treatment group and 25.0% in control group (P<0.05). The median response duration was 5.1 months and 4.2 months in these two groups respectively. The toxicity in the treatment group was less than that of the control group.Conclusion:MVP combination regimen with photohemotherapy can improve the therapeutic effect of advanced NSCLC without increase of toxicity. |
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| Keywords: | Advanced non-small cell lung cancer MVP combination regimen Photohemotherapy |
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