| 高效液相色谱法测定难治性癫痫患者苯妥英钠血药浓度 |
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| 引用本文： | 罗顺德,张先洲,蔡鸿生,潘松青. 高效液相色谱法测定难治性癫痫患者苯妥英钠血药浓度[J]. 中国医院药学杂志, 1991, 0(8) |
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| 作者姓名： | 罗顺德 张先洲 蔡鸿生 潘松青 |
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| 作者单位： | 湖北医学院临床药学研究室 430060(罗顺德，张先洲，蔡鸿生)，湖北医学院临床药学研究室 430060(潘松青) |
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| 摘 要： | 本文选择难治性癫痫患者为对象,用高效液相色谱法测定了该类患者体内苯妥英钠的血药浓度,并按照非线性药物的剂量调整方法制定了给药方案,取得满意疗效。本法灵敏度高、迅速、准确稳定。
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| 关 键 词： | 高效液相色谱 难治性癫痫 苯妥英钠血药浓度 |
The Determination of Serum Concentration of Phenytoin in Intractable Epileptic by HPLC |
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| Lou Shun-de,et al. The Determination of Serum Concentration of Phenytoin in Intractable Epileptic by HPLC[J]. Chinese Journal of Hospital Pharmacy, 1991, 0(8) |
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| Authors: | Lou Shun-de et al |
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| Affiliation: | Lou Shun-de,et al Department of Clinical Pharmaceutic Research,Hubei Medical College,Wuhan 430060 |
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| Abstract: | The serum concentration of phenytion is determined in intractable epilepticby high performance liquid chromatography. The dosage is adjusted according tononlinear pharmacokinetics. The result is satisfied. This method is accurate, rapid,stable and highly sensitive. |
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| Keywords: | High performance liquid chromatography Intractable epilepsy Phenytoin Serum-concentration |
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