单纯淋球菌感染与淋球菌混合其他病原体感染患者的治疗分析

目的 观察和比较"中国疾病预防控制中心"制定的治疗方案(常规方案)对单纯淋球菌感染和淋球菌混合其他病原体感染患者的治疗效果.方法 收集32例单纯淋球菌感染患者和50例混合病原体感染患者(淋球菌合并沙眼衣原体或解脲支原体或梅毒螺旋体感染)的临床资料,回顾患者经常规方案治疗的效果,比较单纯淋球菌感染与混合病原体感染患者临床痊愈所需时间(接受常规方案至获得临床痊愈的时间).结果 所有患者的总体痊愈率为92.4%,其中单纯淋球菌感染患者均获得临床痊愈,混合病原体感染患者的临床痊愈率为84.0%.单纯淋球菌感染和淋球菌混合其他病原体感染患者临床痊愈所需时间平均为(9.4±1.8)d和(9.7±2.3)d,两者比较差异无统计学意义(P＞0.05).结论 接受常规方案治疗的淋球菌混合其他病原体感染患者的临床痊愈时间与单纯淋球菌感染患者相当,提示常规方案亦适用于混合病原体感染患者.

Therapeutic effects in patients with single gonococcal infection or with infections of gonococci mixed with other pathogens

Objective To investigate the therapeutic effects of regimen designed by Chinese Center for Disease Control and Prevention (conventional regimen) on patients with single gonococcal infection or with infections of gonococci mixed with other pathogens. Methods The clinical data of 32 patients with single gonococcal infection and 50 patients with gonococcal infection mixed with the other pathogen infection (gonococcal infection mixed with Chlamydia trachomatis infection, mycoplasma urealytium infection or treponema pallidum infection) were collected, the therapeutic effects of conventional regimen were retrospectively analysed, and time spent for clinical recovery (from the initiation of conventional regimen to clinical recovery) was compared between patients with single gonococcal infection and those with gonococcal infection mixed with the other pathogen infection. Results The total clinical recovery rate was 92.4%, with 100% for patients with single gonococcal infection and 84.0% for those with gonococcal infection mixed with the other pathogen infection. Time spent for clinical recovery for patients with single gonococcal infection and those with gonococcal infection mixed with the other pathogen infection was (9.4±1.8) d and (9.7±2.3) d, respectively, and there was no significant difference between them (P>0.05). Conclusion Time spent for clinical recovery for patients with gonococcal infection mixed with the other pathogen is similar to that for patients with single gonococcal infection, indicating that conventional regimen is also suitable to patients with gonococcal infection mixed with the other pathogen infection.