原发性肝癌切除术后复发的肝移植治疗

目的总结原发性肝癌切除术后复发行肝移植治疗的经验。方法2002年8月至2004年11月上海交通大学医学院附属瑞金医院对4例肝癌切除术后复发病例（其中1例合并急性肝功能衰竭）行同种异体肝移植治疗。结果3例移植术后已分别无瘤存活17个月、12个月和27个月至今。1例术后第3天死于多器官功能衰竭。结论对原发性肝癌切除术后复发病例的肝移植治疗，小肝癌切除后复发肿瘤仍符合Milan标准者有着良好的预后；个别合并门静脉癌栓者预后较好；合并急性肝功能衰竭者应相当谨慎。

Liver transplantation for recurrence of primary liver carcinoma after resection ( a report of 4 cases)

Objective Summary the experience of 4 cases liver transplantation for recurrence of primary liver carcinoma after resection.Methods From August 2002 to November 2004,4 patients have underwent liver transplantation because of recurrence of liver carcinoma after resection (one case complicated acute hepatic function failure) in Rui Jin hospital affiliated of the Shang Hai Jiao Tong University.Results Up uo now,the disease free survival of 3 patients was 17,12,27 months respectively.1 patient has died of multiple organ failure on 3th day after liver transplantation.Conclusion Liver transplantation was the effective treatment for the recurrence after resection of small liver carcinoma and which was coincidence with Milano criteria yet;after liver transplantation,few patients with portal vein tumor thrombi has good prognosis also;but it should be especially prudent for the patients with acute liver function failure after resection of primary liver carcinoma.