职业性急性环氧乙烷中毒临床分析

目的研究环氧乙烷急性中毒的临床特点及从环氧乙烷中毒事故中吸取经验、教训。方法将辽宁省抚顺市职业病防治院收治的2例接触环氧乙烷造成中毒的病例资料及事故原因进行综合分析。结果环氧乙烷水溶液喷出后经呼吸道和皮肤吸收引起急性中毒，主要造成皮肤灼伤，心肌损害，胰腺损害，肝功能障碍，精神障碍。目前治疗尚无特效解毒剂，经采取综合有效的治疗措施，2例患者除遗留灼伤后皮肤色素沉着斑片、斑痕外均痊愈出院。结论中毒发生后及时进行皮肤冲洗、催吐非常重要，治疗及时预后良好。

Clinical Analysis of Occupational Acute Ethylene Oxide Poisoning

[ Objective] To study the clinical characteristics of acute occupational ethylene oxide poisoning and get experience and lessons from the accident of acute occupational ethylene oxide poisoning. [ Methods] Comprehensive analysis was made on the medical records and causes of two ethylene oxide poisoning cases in the hospital. [ Results ] The solution of ethylene oxide led to acute ethylene oxide poisoning when it was absorbed by the respiratory system and skin, which induced skin burn, myocardial injury, pancreas injury, liver function disorder and psychopathy. There are not specific antidotes to cure ethylene oxide poisonings up to now, but through comprehensive treatment, the two patients got recovery and were discharged from hospital only with some pigmentation and cicatrice left on the skin. [ Conclusion] It is very important to cleanse the skin and urge vomit after the poisoning; the patients will have a good prognosis if they can be treated promptly.