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含左氧氟沙星方案治疗耐药肺结核疗效观察
引用本文:王伟丽. 含左氧氟沙星方案治疗耐药肺结核疗效观察[J]. 医药论坛杂志, 2007, 28(14): 21-22
作者姓名:王伟丽
作者单位:河南省胸科医院内科,郑州市,450003
摘    要:目的 评价左氧氟沙星对耐多药肺结核(MDR-TB)的临床疗效.方法 104例MDR-PTB病人随机分为两组,54例应用3HZThTV/12HThTV方案治疗,50例采用3HZThT/12HThT方案治疗.结果 疗程结束时,治疗组痰菌阴转率92.6%明显高于对照组40%.经两年随访,治疗组和对照组细菌学复发率分别为8%和30%.两组间差异有显著性.结论 左氧氟沙星是治疗MDR-PTB的较为有效的药物.

关 键 词:结核/肺  耐多药  左氧氟沙星
文章编号:1672-3422(2007)14-0021-02
修稿时间:2007-03-25

Observation of Therapeutic Effects of Levofloxacin Regimen on Multi- drug Resistant Pulmonary Tuberculosis
WANG Weili. Observation of Therapeutic Effects of Levofloxacin Regimen on Multi- drug Resistant Pulmonary Tuberculosis[J]. Journal of Medical Forum, 2007, 28(14): 21-22
Authors:WANG Weili
Affiliation:Henan Provincial Chest Hospital, Zhengzhou 450003, China
Abstract:Objective To evaluate the effect of chemotherapy with Levofloxacin multi-drug resistant tuberculosis(MDR-TB).Methods 104 cases with MDR-TB were divided randomly into two groups.54 cases were treated with the regimen of 3HZThTV/12HThTV.50 cases were treated with 3HZThT/12HThT.Results At the end of treatment,the rate of sputum negative conversion in the treatment group 92.6% were higher than that in the control group(40%).During two years follow up,the bacteriological relapse rate were found to be 8% in treatment group and 30% in control group.Comparing the two groups,there was an obvious difference.Conclusion Levofloxacin was an effective drug in patients with MDR-TB.
Keywords:Tuberculosis/Pulmonary    Muhidrug resistant    Levofloxacin
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