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D-二聚体在妇科术后下肢深静脉血栓形成溶栓中的意义
引用本文:韩素新,陈素兰,朱洁茹. D-二聚体在妇科术后下肢深静脉血栓形成溶栓中的意义[J]. 华北煤炭医学院学报, 2009, 11(4): 473-474
作者姓名:韩素新  陈素兰  朱洁茹
作者单位:华北煤炭医学院附属医院妇产科,河北唐山,063000
摘    要:
①目的 探讨下肢深静脉血栓形成(DVT)的溶栓治疗过程中血浆D-二聚体的变化、疗效评价以及预后判断.②方法 用胶体金免疫渗透试验(GIA)法测定26例DVT患者在溶栓治疗过程中不同时间(治疗前、治疗后第1天、第3天、1周、2周、治疗结束后)的D-二聚体含量.③结果 溶栓治疗后D-二聚体水平显著性升高,峰值出现时间平均为2天.治疗后1周D-二聚体下降至溶栓前水平,治疗后2周D-二聚体与溶栓前比较差异有显著性.治疗结束后D-二聚体降至正常范围.④结论 动态监测D-二聚体的水平变化可以作为DVT溶栓治疗时评价疗效及判断预后的特异性指标.

关 键 词:下肢深静脉血栓形成  溶栓治疗  D-二聚体

Significance of D-dimer in thrombolytic therapy of lower extremity deep venous thrombosis after gynecologic operation
HAN Suxin,CHEN Sulan,ZHU Jieru. Significance of D-dimer in thrombolytic therapy of lower extremity deep venous thrombosis after gynecologic operation[J]. Journal of North China Coal Medical College, 2009, 11(4): 473-474
Authors:HAN Suxin  CHEN Sulan  ZHU Jieru
Affiliation:Department of Gynecology;The Affiliated Hospital of North China Coal Medical Univesity;Tangshan 063000;China
Abstract:
Objective To investigate the change of D-dimer,curative effect evaluation and prognostic judgement in thrombolytic therapy of lower extremity deep venous thrombolsis(DVT).Methods Gold colloids immunofiltration assay(GIA) was used to detect D-dimer in the plasma in 26 patients with DVT at different times during thrombolytic treatment using urokinase (before treatment,1 day,3 days,1 week,2 weeks after the beginning of the treatment and in the end).Results D-dimer levels were increased significantly after thro...
Keywords:Lower extremity deep venous thrombosis.Thrombolytic therapy. D-dimer  
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