Circadian variation in BDNF mRNA expression in the rat hippocampus |
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Authors: | Schaaf M J Duurland R de Kloet E R Vreugdenhil E |
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Affiliation: | Division of Medical Pharmacology, Sylvius Laboratories, Leiden/Amsterdam Center for Drug Research, 2300 RA, Leiden, Netherlands. |
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Abstract: | BDNF mRNA levels in the hippocampus were studied during the circadian cycle by in situ hybridization. These levels display a circadian pattern, which may be due to regulation by corticosterone. This may have consequences for hippocampal functioning at different time points of the circadian cycle. |
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