Effect of amnion membrane transplantation on corneal neovascularization in 10 patients with alkali burn |
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Authors: | Lan Yin and Yu-Li Pi |
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Institution: | Department of Ophthalmology, the First Affiliated Hospital of General Hospital of PLA, Beijing 100048, China and Department of Ophthalmology, the First Affiliated Hospital of General Hospital of PLA, Beijing 100048, China |
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Abstract: | By observing clinical cases, we studied the curative effect of amnion membrane transplantation on decreasing corneal neovascularization (CNV). It was a non-randomized retrospective case-control study. Among 17 cases (21 eyes) of third-degree alkali burns from 2007 to 2010, 10 cases (12 eyes) were performed with amnion membrane transplantation operation, and others were not. Amnion membrane transplantation was performed at the 3rd day after burn in the treatment group. Areas of CNV in double groups were measured at the 14th day and 60th day after burn. Area of CNV in the treatment group was (66.207±7.251)mm2 at the 14th day after burn, and was 18.27% lower than that in the control group. Area of CNV in the treatment group was (120.046±13.812)mm2 at the 60th day after burn, and was 11.35% lower than that in the control group. There was both statistical significance (P<0.05). Amnion membrane transplantation operation can inhibit the growth of corneal neovascularization induced by alkali burn. |
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Keywords: | amnion transplantation eye burn corneal neovascularization |
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