准分子激光治疗白癜风的临床疗效与安全性研究 |
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引用本文: | 陶莉,项蕾红,金以,卢忠,郑志忠. 准分子激光治疗白癜风的临床疗效与安全性研究[J]. 国际皮肤性病学杂志, 2008, 35(1): 204-206. DOI: 10.3760/cma.j.issn.1673-4173.2009.04.002 |
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作者姓名: | 陶莉 项蕾红 金以 卢忠 郑志忠 |
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作者单位: | 复旦大学附属华山医院皮肤科,上海,200040; |
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摘 要: | Objective To assess the efficacy and safety of 308 nm excimer laser in the treatment of different types of vitiligo at different stages. Methods A total of 128 patients with vitiligo, who had 317 depigmented patches, were recruited in this study and treated with 308 nm excimer laser once a week for at least 8 weeks. The degree of repigmentation was evaluated and adverse effects were recorded at the end of every treatment and last treatment. Results All patients received efficacy and safety evaluation. Of the 317 patches, 97.5% achieved repigmentation at different degrees, 71.8% got more than 25% repigmentation, and 50.8% got more than 75% repigmentation. The degree of repigmentation increased with the number of treatments. A better response was observed in the lesions on the face and neck than those on the mink and limbs, and in short-duration (<1 year) lesions than in long-duration (≥1 year) lesions. And the lesions on extremities and mueosa showed a poorer response compared with those at other sites. There was no statistical difference in clinical efficacy between active vitiligo and stable vitiligo, or between adults and children. Moreover, the treatment was well tolerated. Conclusion 308 nm excimer laser is effective in the treatment of vitiligo with rapid onset, favorable tolerability and few adverse effects.
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关 键 词: | 白癜风 准分子激光 治疗结果 |
Efficacy and safety of 308 nm excimer laser in the treatment of vitiligo |
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Abstract: | |
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Keywords: | VitiligoExcimer laserEfficacy |
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