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香附四物汤对原发性痛经(气滞血瘀型)凝血功能的影响
引用本文:董其虎,王佩娟. 香附四物汤对原发性痛经(气滞血瘀型)凝血功能的影响[J]. 中医药导报, 2012, 18(2): 34-35
作者姓名:董其虎  王佩娟
作者单位:1. 南京中医药大学,江苏,南京,210046
2. 江苏省中西医结合医院,江苏,南京,210028
基金项目:江苏省高校自然科学重大基础研究项目
摘    要:目的:观察香附四物汤对气滞血瘀型原发性痛经患者凝血功能的影响并评价其临床疗效.方法:选取12例气滞血瘀型原发性痛经患者,口服香附四物汤配方颗粒治疗3个月经周期,观察治疗前后临床疗效,并检测治疗前和治疗第2月经周期、第3月经周期月经来潮12小时内凝血功能.结果:经香附四物汤治疗后,12例患者总有效率为83.3%.治疗后凝血功能示APTT时间延长,与治疗前比较,差异有统计学意义(P<0.05),其余项目治疗前后无明显变化(P>0.05).结论:香附四物汤对气滞血瘀型原发性痛经患者疗效较好,且能延长APTT,可能为其治疗本病机制之一.

关 键 词:香附四物汤  气滞血瘀  原发性痛经  凝血功能  APTT

Xiangfu siwu decoction on primary dysmenorrhea (qi stagnation and blood stasis type) effect on blood coagulation function
Dong Qihu,Wang Peijuan. Xiangfu siwu decoction on primary dysmenorrhea (qi stagnation and blood stasis type) effect on blood coagulation function[J]. GUIDING JOURNAL OF TCM, 2012, 18(2): 34-35
Authors:Dong Qihu  Wang Peijuan
Affiliation:1.Nanjing University of Chinese Medicine 2009 graduate student,Jiangsu Nanjing 210046; 2.Jiangsu province traditional chinese and western medicine hospital,Jiangsu Nanjing 210028)
Abstract:Objective: To observe the curative effect of Xiangfu Siwu Decoction’s treatment on primary dysmenorrhea of syndrome of qi stagnation and blood stasis and to evaluate Xiangfu Siwu Decoction’s impact on blood coagulation.Method: choosing 12 patients suffered from primary dysmenorrhea of syndrome of qi stagnation and blood stasis,taking Xiangfu Siwu granular,Observing the curative effect,and detecting the vary of PT、INR、APTT、TT、FIB before treatment、the 2nd and the 3rd Menstrual cycle within 12 hours.Result: Xiangfu Siwu Decoction have multiple significant effect on primary dysmenorrhea of syndrome of qi stagnation and blood stasis,which can prolong APTT,compared with no vary on other programs.
Keywords:Xiangfu Siwu Decoction  qi stagnation and blood stasis  primary dysmenorrhea  blood coagulation
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