左旋氨氯地平与硝苯地平治疗轻中度高血压病的疗效观察

目的评价左旋氨氯地平对轻中度高血压病患者的降压疗效,并与硝苯地平对比。方法采用随机分组对照方法,将100例轻中度高血压病患者分为治疗组(50例),用苯磺酸左旋氨氯地平片2.5mg,qd,po;对照组(50例),硝苯地平片10mg,tid,po。两组疗程均为12周。观察降压效果和临床不良反应。结果 两组患者用药第一周后均能有效控制血压,随着用药时间延长血压平稳下降,治疗组与对照组比较差异有显著性。对照组不良反应高于治疗组。结论 左旋氨氯地平与硝苯地平均能有效降压,前者优于后者,不良反应较少,临床耐受性较好。

Curative Effect Comparison between L-amlodipine and Nifedipine in Treating Patients with Mild to Moderate Hypertension

Objective To evaluate the antihypertensive effect of L-amlodipine on patients with mild to moderate hypertension and to compare it with that of nifedipine.Methods 100 cases with mild to moderate hypertension were randomly divided into 2 groups: treatment group and control group,50 cases in each;patients in treatment group received Levamlodipine Besylate 2.5mg,qd,po.while patients in control group received nifedipine 10mg,tid,po.;the course in both groups were 12 weeks;the antihypertensive effect and side ef...