一种稳定型过氧乙酸的消毒相关性能观察

目的观察一种稳定型过氧乙酸消毒液的杀菌效果及其他消毒相关性能。方法通过理化分析法和悬液定量杀菌试验及动物试验方法,对该消毒液杀菌效果和安全相关性能进行了实验室试验。结果该消毒液中过氧乙酸含量为168 g/L。用浓度为336 mg/L的该过氧乙酸水溶液作用10 min,对悬液内金黄色葡萄球菌和大肠杆菌均可达到完全杀灭。用相同浓度的过氧乙酸水溶液擦拭物体表面并保持作用10 min,对物体表面自然菌平均杀灭对数值>1.00。以该消毒液5倍使用浓度对小鼠急性经口毒性试验LD50值为>5 000 mg/kg(体重),对小鼠骨髓嗜多染红细胞微核试验结果阴性。结论该稳定型过氧乙酸消毒液对细菌繁殖体杀灭效果较好,属无毒级物质。

OBSERVATION ON DISINFECTION PROPERTIES OF A STABLE PERACETIC ACID

Objective To observe the germicidal efficacy and other disinfection properties of a kind of stable peracetic acid.Methods Physical and chemical analysis,suspension quantitative bactericidal test and animal test were carried out to observe the properties on bactericidal effect and safe of this disinfection.Results This disinfectant contained 168 g/L peracetic acid.Escherichia coli and Staphylococcus aureus in suspension were killed completely exposed to 336 mg/L peracetic acid for 10 min.The average killing logarithm value of natural bacteria exposed to this disinfectant with the same concentration wiping the objects surface for 10 min was >1.00.The acute oral LD50 of this disinfectant with 5 times concentration in mice was 500 0mg/kg·bw.It could not cause micronucleus formation in mouse bone marrow polychromatic erythrocytes.Conclusion This stable peracetic acid disinfectant has good germicidal efficacy on bacteria vegetative and has no toxicity.