Cardiovascular complications in Kawasaki disease: coronary artery lumen and long-term consequences |
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| Affiliation: | 1. Institute of Experimental and Clinical Pharmacology and Toxicology, Medical Faculty Mannheim, Universität Heidelberg, Germany;2. Department of Pharmacology and Therapeutics, University College Cork, Cork, Ireland;3. Division of Nephrology, Department of Internal Medicine III, Faculty of Medicine, Technische Universität Dresden, Germany;4. Department of Obstetrics, Division of Women and Child Health, Universität Leipzig, Leipzig, Germany;5. Division of Cardiology, University of California, San Diego, USA;1. Division of Echocardiography, Women and Children''s Hospital of Qinghai Province, Xining, Qinghai, China;2. Statistician, Data Center of Congenital Heart Surgeons'' Society, Hospital for Sick Children, Toronto, Ontario, Canada;3. Clinical Physiology Research Center, Capital Institute of Pediatrics, Beijing, China |
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| Abstract: | Kawasaki disease (KD) is an acute vasculitis syndrome in infants and young children which affects small- and medium-sized arteries, particularly the coronary arteries. It has replaced rheumatic fever as the most common cause of acquired heart disease in children. In this article, we review the spectrum of the cardiovascular complications, the natural history or fate of coronary aneurysms and long-term issues, the impact on cardiovascular and overall mortality, and the issues in coronary artery disease in the adulthood, from our experience based on 2117 patients over the past 30 years. |
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