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自身免疫病患者碱性磷酸酶测定的意义
引用本文:郭大文,胡华,孟冬娅,于笑难,罗军,左伟. 自身免疫病患者碱性磷酸酶测定的意义[J]. 现代检验医学杂志, 2001, 16(1): 54-55
作者姓名:郭大文  胡华  孟冬娅  于笑难  罗军  左伟
作者单位:沈阳军区总医院检验科,
摘    要:
检测了50例自身免疫病患者的血清ALP、免疫球蛋白、补体及ENA多肽抗体。结果显示与对照组相比,自身免疫病患者的ALP活性升高(P<0.05),IgG显著升高(P<0.01),IgA、IgM升高(P<0.05),C

关 键 词:碱性磷酸酶;自身免疫病
文章编号:1005-1716(2001)01-054-02
修稿时间:2000-06-01

Meassurement of AlkalinePhosphatase in the Serum of Patients With Autoimmune Diseases
GUO Da wen HU Hua MENG Dong ya YU Xiao nan LUO Jun ZUO Wei. Meassurement of AlkalinePhosphatase in the Serum of Patients With Autoimmune Diseases[J]. Journal of Modern Laboratory Medicine, 2001, 16(1): 54-55
Authors:GUO Da wen HU Hua MENG Dong ya YU Xiao nan LUO Jun ZUO Wei
Abstract:
We have determined total alkaline phosphatases(ALP)activity,immunoglobulin, complement and autoantibodies against extractable n uclear antigen(ENA).Compared with healthy controls,ALP activitis increased (P<0.05)and IgG was notably high (P<0.01)in patients with autoimmune diseases(AID).IgA and IgM were higher,while C3 and C4 were lower in patienst than in controls.Autoantibodies against ENA were found in 82% patients with AID.The ALP activities in RA patients with abnormal RF test(≥45IU/ml) was significan tly higher(P<0.05)than in RA patients with normal RF test.The ALP activities were higher (P<0.05) in SLE patients with active disease than in SLE patients who were in remission.The resulfs indicated that ALP activities might be useful in diagnosis of AID combined with other examines.
Keywords:Alkaline phosphstase  Autoimmune diseases
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