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口服Sumatriptan治疗偏头痛的临床评价
引用本文:福源,谈永基. 口服Sumatriptan治疗偏头痛的临床评价[J]. 中国临床神经科学, 1994, 2(2): 97-99
作者姓名:福源  谈永基
作者单位:上海第二军医大学长征医院神经科 200003(邵福源,黄流清,吴萍嘉),上海医科大学华山医院神经科 200040(谈永基),上海第二医科大学瑞金医院神经科 200025(余慧贞,章瑛),上海第二医科大学仁济医院神经科 200001(蔡琰,戴志仙),上海第二医科大学仁济医院神经科 200001(苗玲)
摘    要:
本文报告口服Sumatriptan 100mg对偏头痛急性发作119例次的治疗结果。治疗后4h内显效91例次(76.5%),好转16例次(13.4%),无效12例次(10.1%),总有效率为89.9%。对偏头痛伴随症状恶心、呕吐和畏光、畏声的缓解率分别为94.2%、96%和94.3%。

关 键 词:偏头痛  Sumatriptan  药物治疗  5-羟色胺受体

Clinical Evaluation of Oral Sumatriptan in Treatment of Migraine Attacks
Shao Fu-Yuan,Huang Liu-Qing,Wu Ping-Jia. Clinical Evaluation of Oral Sumatriptan in Treatment of Migraine Attacks[J]. Chinese Journal of Clinical Neurosciences, 1994, 2(2): 97-99
Authors:Shao Fu-Yuan  Huang Liu-Qing  Wu Ping-Jia
Affiliation:Shao Fu-Yuan,Huang Liu-Qing,Wu Ping-Jia Department of Neurology .Changzheng Hospital,Second Military Medical UniversityTan Yong-Ji Department of Neurology,Huashan Hospital .Shanghai Medical UniversityYu Hui-Zhen,Zhang Ying Department of Neurology,Ruijin Hospital .Shanghai Second Medical UniversityCai Yan,Dai Zhi-Xian,Miao Ling Department of Neurology,Renji Hospital .Shanghai Second Medical University
Abstract:
The efficacy of oral sumatriptan 100mg in treatment of 119 acute migraine attacks was reported. The overall number of attacks in which pain was improved within 4h was 107 (89. 9%). Sumatriptan was also effective in reducing the incidence of nausea .vomiting, and photophobia and phonophobia after treatment. Only a few patients had adverse events during treatment using sumatriptan. It was concluded that the oral sumatriptan was well tolerated and was effective in treatment of migraine attacks. Therefore .sumatriptan is a drug worthy to be further used.
Keywords:Migraine Sumatriptan Drug therapy 5-HT1-like receptors
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