男性吸毒人群甲型肝炎病毒感染状况及其影响因素的研究

目的　了解吸毒人员中甲型肝炎病毒的感染状况 ,为防制甲肝提供科学依据。　方法　采用现况研究 ,通过整群抽样 ,以问卷的方式调查男性吸毒人员 45 2名 ,收集有关资料并采集血标本 45 2份。用酶联免疫吸附试验 (ELISA法 ) ,检测血清中抗 -HAV。采用Chi-square检验和Logistic回归分析对数据进行统计学分析。　 结果　 45 2名男性吸毒人员中检出抗 -HAV阳性 2 91人 ,总感染率为 64 .3 8% ;单因素分析 :不同地区甲肝感染率差异有显著性 (χ2 =7 3 49,P <0 .0 5 ) ;不同文化程度 ,不同年龄组 ,不同职业 ,不同吸毒年限甲肝感染率差异无显著性 (P >0 .0 5 )。多因素分析 :不同地区 ,不同职业 ,是否喝生水的甲肝感染率差异有显著性。　结论　吸毒人群是甲型肝炎感染的高危人群。吸毒人员中甲肝的感染与地区差异、职业及卫生习惯有关

A Prevalence Study of Hepatitis A Virus Infection Among Male Drug Users and the Related Factor

Objective To study the condition of Hepatitis A virus infection among drug users, and to offer epidemiologic information for prevention and control of Hepatitis A. Methods To collect general information of 452 cases through cluster-sampling and questionnaire investigation. To collect serums from the 452 drug users. Examine the anti-HAV by ELLISA test. Analyze the data by Chi-square test and Logistic test. Result Infection of Hepatitis A were identified in 291(64.38%) of 452 drug users as a whole. One-way analysis:The infection rate was highest in the west of Hunan .The infection rates of HAV in different degree of education,vocation and drug taking times were not significant. Logistic analysis: the related factors of HAV infection were region,vocation and uncooked water drinking etc. Conclusion Drug users was a group of high risk of Hepatitis A infection.