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甲状腺球蛋白测定与131I全身显像在甲状腺乳头癌复发监测中的意义
引用本文:周飞华,徐海峰,周润锁,邓敬兰. 甲状腺球蛋白测定与131I全身显像在甲状腺乳头癌复发监测中的意义[J]. 标记免疫分析与临床, 2007, 14(3): 154-155
作者姓名:周飞华  徐海峰  周润锁  邓敬兰
作者单位:第四军医大学唐都医院核医学科,陕西,西安,710038;第四军医大学唐都医院核医学科,陕西,西安,710038;第四军医大学唐都医院核医学科,陕西,西安,710038;第四军医大学唐都医院核医学科,陕西,西安,710038
摘    要:
探讨甲状腺球蛋白(Tg)和131I全身显像(131I-WBS)在甲状腺乳头癌(PTC)复发监测中的意义. 30例PTC患者术后6周,行131I(3.7GBq)首次清除残留甲状腺组织治疗,6个月后再给予131I 治疗1次,治疗中同时测定Tg和进行131I-WBS.结果表明,在首次清除残留甲状腺组织治疗时,显像发现淋巴、肺及骨转移6例,其余转移灶于6个月治疗时发现,有3例患者(10%)Tg测定在正常范围,而131I-WBS出现转移灶,4例患者(13.3%)Tg测定异常,而131I-WBS正常.Tg测定和131I-WBS可作为诊断PTC有无转移的重要指标,二者监测复发应联合应用,可互相补充.

关 键 词:甲状腺球蛋白  碘-131  甲状腺乳头癌
文章编号:1006-1703(2007)03-0154-02
修稿时间:2007-02-26

The Value of Thyroglobulin Measurement and 131I-Whole Body Scan on the Papillary Thyroid Carcinoma with 131I Therapy After Surgical Treatment
ZHOU Fei-hua, XU Hai-feng, ZHOU Run-suo,et al.. The Value of Thyroglobulin Measurement and 131I-Whole Body Scan on the Papillary Thyroid Carcinoma with 131I Therapy After Surgical Treatment[J]. Labeled Immunoassays and Clinical Medicine, 2007, 14(3): 154-155
Authors:ZHOU Fei-hua   XU Hai-feng   ZHOU Run-suo  et al.
Affiliation:Department of Nuclear Medicine, The Fourth Military Medical University, Xian 710038,China
Abstract:
To investigate the value of thyroglobulin(Tg) and ~(131)I-whole body scan(~(131)I-WBS) on the papillary thyroid carcinoma(PTC) with ~(131)I therapy after surgical treatment,30 patients with PTC after surgical treatment were treated with ~(131)I therapy,and treated again after 6 months.The serum Tg levels in patients were measured,and all patients were also performed ~(131)I-WBS.The results showed that 6 patients have been found metastases to lymph,lung and bone in first ~(131)I therapy.The serum Tg levels in 3 patients were normal,but the ~(131)I-WBS results were positive. The serum Tg levels in 13.3% patients were abnormal,but ~(131)I-WBS was negative.The combined measurement of serum Tg level and ~(131)I-WBS could be regarded as important index in the diagnosis of metastases of cancer on the patients with papillary thyroid carcinoma.
Keywords:Thyroglobulin Papillary thyroid carcinoma
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