| 重症急性胰腺炎相关性肾损伤的发病机制及防治 |
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| 引用本文： | 孟中良,张培建. 重症急性胰腺炎相关性肾损伤的发病机制及防治[J]. 国际外科学杂志, 2010, 37(4). DOI: 10.3760/cma.j.issn.1673-4203.2010.04.016 |
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| 作者姓名： | 孟中良 张培建 |
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| 作者单位： | 扬州大学第二临床医学院普外科教研室,扬州,225001;扬州大学第二临床医学院普外科教研室,扬州,225001 |
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| 基金项目： | 扬州市科技计划项目,江苏省卫生厅科研课题 |
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| 摘 要： | 重症急性胰腺炎相关性肾损伤的发病机制尚未完全明确,目前主要有肾脏血流动力学异常、炎性递质与细胞因子释放、肾小管细胞凋亡、肠道细菌和内毒素移位等学说,文中就近年来其发病机制及防治研究进展作一综述.
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| 关 键 词： | 重症急性胰腺炎 肾损伤 发病机制 |
Pathogenic mechanism and protection of renal injury in severe acute pancreatitis |
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| Abstract: | Up to now, we still can not completely clarify the pathogenic mechanism of renal injury in se-vere acute pancreatitis. As for the possible mechanism of its involvement, many theories have been intro-duced, such as hemodynamics of kidney dysfunction, releasing of inflammation transmitters and cytokines, apoptotic cell death of renal tubules and enteric bacteria aversion. This review provides an overview of patho-genic mechanism and protection of renal injury in severe acute pancreatitis. |
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| Keywords: | Severe acute pancreatitis Renal injure Mechanism |
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