肾移植术后带状疱疹的诊断与治疗

免疫抑制剂的使用或免疫抑制过度是器官移植术后病毒感染的最重要原因。３０１例肾移植患者术后３１例发生带状疱疹，发病率为１０．３％，发病时间以术后１～２年间最多见，多伴有细胞免疫功能下降。治疗包括抗病毒药物应用、调整免疫抑制剂方案、防止合并细菌感染和对症处理等四个方面。认为阿昔洛韦抗病毒效果较好，而适当减少免疫抑制剂的用量则是治疗的关键

Herpes zoster in kidney transplant recipients

Application of immunosuppressive agents of over-immunosuppressivement is the most main cause of viral infection in organ transplant recipients. Of 301 patients receiving renal transplantation, 31 cases were diagnosed having zoster postoperatively with the incidence being 10.3%. Most of the 31 cases of zoster were found during 1 to 2 years after operation and associated with an insufficient cellular immunity function. The clinical manifestation, the diagnosis of zoster and the treatment are presented. Treatment of herpes zoster included antivirotic, adjustment of immunosuppressive agents, antibiotic and sympomatic treatment. Acyclovir was considered to be an effective antivirotic and the key for treatment was to properly decrease the dosage of immunosuppressive agents.