上海市宝山区肺癌危险因素的病例对照研究

[目的]探讨室内装修及其他生活危险因素与肺癌的关系。[方法]采用1：1配对的病例对照研究方法,以2007年确诊的163例肺癌患者为病例组,选择在年龄、性别、住址方面相匹配的非肿瘤患者为对照组,进行条件Logistic回归分析。[结果]多因素分析结果存在统计学意义的因素包括肿瘤家族史（OR=4.090,P=0.001）、被动吸烟（OR=2.528,P=0.009）、住房10年内有过装修（OR=2.074,P=0.039）、室内经常通风（OR=0.160,P=0.028）、室内种植绿色植物（OR=0.483,P=0.027）和使用实木地板（OR=0.487,P=0.045）。[结论]有肿瘤家族史、被动吸烟和曾室内装修是肺癌的危险因素,室内经常通风、种植绿色植物、使用实木地板是肺癌的保护性因素。

A Case-control Study on the Risk Factors of Lung Cancer in Baoshan District of Shanghai

[ Objective] To study whether the indoor decoration and other factor in living is risk factor of lung cancer. [Methods] A matched case-control study was conducted in 163 pairs of lung cancer cases and control in Baoshan District, 2007. The odds ratio（OR）was analyzed and checked with conditional logistic regression analysis.[ Results] The results showed that the important risk factors of lung cancer included ：family history of cance（rOR = 4.090, P = 0.001）, passive smoking（OR = 2.528, P = 0.009）, house decoration in past 10 years（OR = 2.074, P = 0.039）, sufficient indoor ventilation（OR = 0.160, P = 0.028）, indoor green plantation（OR = 0.483, P = 0.027）, better material and type of floor（OR = 0.487, P = 0.045）.[ Conclusion] Family cancer history, passive smoking and house decoration with faulty material were risk factors of lung cancer, while sufficient indoor ventilation, indoor green plantation were protective factors against lung cancer.