首页 | 本学科首页   官方微博 | 高级检索  
     


The Iml3 protein of the budding yeast is required for the prevention of precocious sister chromatid separation in meiosis I and for sister chromatid disjunction in meiosis II
Authors:Ghosh  Santanu Kumar  Sau   Soumitra  Lahiri   Sudeshna  Lohia   Anuradha  Sinha   Pratima
Affiliation:(1) Department of Biochemistry, Bose Institute, Kolkata, 700 054, India;(2) Present address: Department of Molecular Genetics and Microbiology, University of Texas at Austin, 24th Street and Speedway, ESB 426, Austin, TX 78712, USA
Abstract:
The mitotic kinetochore of the budding yeast contains a number of proteins which are required for chromosome transmission but are non-essential for vegetative growth. We show that one such protein, Iml3, is essential for meiosis, in that the absence of this protein results in reduced spore viability, precocious sister chromatid segregation of artificial and natural chromosomes in meiosis I and chromosome non-disjunction in meiosis II.
Keywords:Meiosis I  Yeast mutant  iml3  Precocious separation of sister chromatids
本文献已被 PubMed SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号