负压封闭引流在感染创面的局部应用

目的:评估负压封闭引流术(VSD)在感染创面局部应用的效果.方法:挑选18名创面感染患者,平均年龄(45±10)岁,其中11名男性,7名女性,感染创面部位:手部8例,小腿5例,臀部3例,骶部2例,创面使用100～125mmHg负压持续吸引2天,然后间歇吸引,平均负压吸引时间为(9±2)天,测量VSD治疗前后创面大小,随访平均时间为(11±6)个月.结果:创面平均吸引出100±50ml液体,组织水肿及创面引流得到解决,创面清洁干燥,其中15例患者通过运用抗生素及负压吸引术,创面已达到临床愈合,细菌培养阴性,通过负压治疗创面大小从(28±9)cm2减少至(12±8)cm2(P<0.05),只有6例需要进一步外科干预达到闭合创面,2例患者使用负压吸引后感觉疼痛.结论:与传统治疗方法相比,除了VSD本身对创面快速愈合的优点外,还提供了一个快速、舒适的条件.

Use of vacuum sealing drainage in the topical treatment of wound infections

Objective To evaluate the results of vacuum sealing drainage in the topical treatment of wound infections.Methods Vacuum therapy was performed in 18 patients(11males,7 females;mean age 45±10 years) using the VSD system(vacuum sealing drainage) for the treatment of wound infections.Infective wounds were in the hand(n=8),crus(n=5),croup(n=3),and sacrum(n=2).The wounds were treated with a negative pressure of 100～125 mmHg applied continuously for the first two days,and then intermittently for the following days.The mean duration of vacuum therapy was(9±2) days.Measure wound surface areas before and after vacuum therapy.The mean follow-up period was 11±6 months.Results The mean amount of discharge from the wound was(100±50)ml.Tissue edema and discharge problems were resolved in all the wounds and a hygienic and dry-looking surgical site was attained.In 15 patients,clinical and bacteriologic eradication of infections was achieved at the surgical site through antibiotic use and vacuum therapy.The mean wound area showed a significant reduction from(28±9)cm2 to(12±8)cm2 following vacuum therapy(P<0.05).Only six patients required further surgical interventions for the closure of wound site.Two patients(11.8%) complained of pain associated with vacuum application.Conclusion Besides its topical advantages in the care of infected wounds,vacuum sealing drainage provides a more rapid and comfortable treatment opportunity,representing a reliable alternative to conventional wound care methods.