金天格胶囊治疗骨质疏松性骨折50例临床研究

目的 观察金天格胶囊( JTG)对于骨质疏松性骨折的临床疗效.方法 随机选取本院骨科门诊X线诊断脊椎骨折100例,分为治疗组与对照组.纳入标准为X线平片和双能X线(DEXA)检测.治疗组:服用金天格胶囊,每日3次,每次3粒,连服3月.对照组:单服钙尔奇D每日1次,每次1粒,连服3月.用药前后测量双能X线(DEXA)骨密度仪进行骨密度测定和生化检测.碱性磷酸酶(ALP)用生化法检查,Beckman公司全自动生化分析仪测定,抗酒石酸盐酸性磷酸酶(TRAP)采用酶法测定.治疗结果进行痊愈,显效,有效,无效评价,统计学方法采用Ridit分析.结果 治疗组与对照组治疗前后骨密度变化比较,金天格胶囊治疗组总有效率94％,对照组总有效率56％,治疗组优于对照组.结论 金天格胶囊可以逐渐使骨质疏松性骨折所致疼痛改善并消失,骨痂形成加快,并有显著治疗骨质疏松性骨折的疗效.

The clinical research of Chinese traditional medicine Jintiange capsule for the treatment of osteoporotic fracture in 50 patients

Objective To observe the clinical efficacy of Jintiange capsule(JTG) for the treatment of osteoporotic fracture.Methods One hundred patients with vertebral fracture diagnosed with X-ray in orthopedic clinic in our hospital were randomly selected and divided into the treatment group and the control group.The inclusive criteria of osteoporotic fracture patients were X-ray and DEXA measurement.Patients in the treatment group were treated with JTG capsule 3 times per day and 3 capsules each time for 3 months.Patients in the control group were treated with calcium once per day and 1 capsule each time for 3 months.Bone mineral density(BMD) was measured before and after the treatment using DEXA and biochemical measurement was also conducted.ALP was measured using biochemical method with an automatic biochemistry analysis machine(Beckman Co.).TRAP was measured using enzyme based method.The therapy results were assessed as recovery,obviously effective,effective,and non-effective.Ridit analysis was used as statistical method.Results The changes of BMD before and after treatment both in the treatment group and control group showed that the total effective rate in the treatment group(94%) was better than that in the control group(56%).Conclusion JTG capsule can continually relieve or eliminate the pain caused by osteoporotic fracture and can accelerate the formation of bone callus.The efficacy of JTG capsule for the treatment of osteoporotic fracture is significant.