肝硬化患者红细胞参数测定及临床意义

目的观察肝硬化患者红细胞参数变化，探讨其临床意义。方法检测45例肝硬化患者（肝硬化组）红细胞计数（RBC）、血红蛋白含量（Hb）、红细胞比积（HCT）、平均红细胞体积（MCV）、红细胞体积分布宽度（Row），并与42例健康者（对照组）进行比较。结果与对照组比较，肝硬化组的RBC、HCT、Hb均显著下降（P〈0．05），MCV、RDW显著升高（P〈0．05，P〈0．01），并且随着Child—Pugh积分的增加，红细胞参数的异常程度逐渐加重（P〈0．05，P〈0．01）。结论肝硬化患者存在红细胞异常，红细胞参数可以反映肝病的肝损程度和病情轻重。

The changes of red blood cell parameters and its clinical significance in patients with hepatic cirrhosis

Objective To observe the changes of red blood cell parameters in patients with hepatic cirrhosis and study its clinical significance. Methods Red blood cell count （RBC）, hemoglobin （Hb）, hematocrit （HCT）, mean cell volume（MCV） ,red cell distribution width（RDW） of 45 patients with hepatic cirrhosis（ the study group） and 42 healthy people （the control group） were examined and analyzed by test. Results Compared with the control group, RBC, Hb and HCT of the study group descended evidently （P 〈 0. 05 ）, and MCV, RDW increased significant- ly. With the increases of the Child-Pugh integrate, the abnormality of the red blood parameters aggravated gradually（P 〈 O. 05, P 〈 0. 01 ）. Conclusion There is abnormality of red blood ceil parameters in patients with hepatic cirrhosis, some red blood cell parameters may reflect the pathogenetic condition and damage degree of liver disease.