| 肺动脉高压的治疗现状与进展 |
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| 引用本文： | 张清友,杜军保.肺动脉高压的治疗现状与进展[J].临床儿科杂志,2010,28(7). |
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| 作者姓名： | 张清友 杜军保 |
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| 作者单位： | 北京大学第一医院儿科,北京,100034 |
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| 摘 要： | 肺动脉高压是一种威胁儿童生命的严重疾病.近10年来有关肺动脉高压的治疗取得了很大进展.目前有3类药物(前列环素类药物、内皮素受体拮抗剂及5型磷酸二酯酶抑制剂)在肺动脉高压患者治疗研究中取得很大进步,但多中心的随机对照研究尚待加强.房间隔切开术和心肺移植对于内科治疗无效的肺动脉高压患儿有一定疗效.
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| 关 键 词： | 肺动脉高压 儿童 治疗 |
Progress on treatment or pulmonary hypertension in children |
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| ZHANG Qing-you,DU Jun-bao.Progress on treatment or pulmonary hypertension in children[J].The Journal of Clinical Pediatrics,2010,28(7). |
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| Authors: | ZHANG Qing-you DU Jun-bao |
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| Institution: | ZHANG Qing-you,DU Jun-bao(Department of Pediatrics,Peking University First Hospital,Beijing 100034,China) |
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| Abstract: | Pulmonary hypertension(PH) is a life-threatening disease in children.In the last decade the treatment of PH has improved.Three classes of drugs(prostanoids,endothelin receptor antagonists,and phosphodiesterase inhibitors) have been extensively studied for treatment of PH.However,there are no data from multicenter randomized clinical trial.Atrial septostomy and lung or combined heart and lung transplantation is considered as the last chance for non-responders to medical treatment. |
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| Keywords: | pulmonary hypertension children treatment |
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