顺铂个体化给药的消化道反应分析 |
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引用本文: | 李明泉,胡月珍,张再军,杨华清. 顺铂个体化给药的消化道反应分析[J]. 四川医学, 2009, 30(3): 376-377 |
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作者姓名: | 李明泉 胡月珍 张再军 杨华清 |
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作者单位: | 广元市中心医院肿瘤科,四川,广元,628017;广元市中心医院肿瘤科,四川,广元,628017;广元市中心医院肿瘤科,四川,广元,628017;广元市中心医院肿瘤科,四川,广元,628017 |
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摘 要: | 目的观察个体化顺铂给药的消化道反应与有关资料比较分析。方法回顾性收集了我院2000年1月~2006年1月晚期姑息治疗原则,含顺铂方案的86例共140周期的临床资料,按70mg/m^2计算出周期顺铂总量,首剂均为20mg。静脉避光滴注。第2天用量根据当日晨消化道反应决定用量,无反应或Ⅰ^*消化道反应加倍顺铂量为40mg,逐日递加至60mg/d为限。每日常规给予胃复安10mg或格拉斯琼3mg预处理。结果140个周期含顺铂方案消化道反应为55%(77/140).与有关报道〉90%明显下降。表明个体顺铂给药患者消化道反应具有较好耐受性,提高了治疗期生存质量。
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关 键 词: | 个体化给药 顺铂 消化道反应 |
The nalysis of digestive tract rcaction of C-DDP dministrated individually |
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Affiliation: | LI Ming-quan, HU Yue-zhen, ZHANG Zai-jun, et al. (The Central Hospital of Guangyuan, Guangynan, Sichuan 628017, China) |
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Abstract: | Objective To investigate the digestive tract reaction of C-DDP administrated individually. Methods 86 cases treated by C-DDP administrated individually were studied retrospectively from January 2000 to January 2006. Results the ineidenee of digestive tract reaction of C-DDP administrated indeividually are 55 % (77/140) . Conclusion The C-DDP administrated individually has better toleamce than administrated routinely, and enhanees life quality in treatment period. |
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Keywords: | individual administration C-DDP digestive tract reaction |
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